Saturday 10 January 2015

Effect of Haritaki (Terminalia chebula Retz) in hypercholesterolemia.


 Title:-Effect of Haritaki (Terminalia chebula Retz) in hypercholesterolemia.

         
          Dr. N. K. Arora had submitted his dissertation to Pune University in the year 2001 for the degree Ph.D. (Sharir Kriya) . His guide was Prof. Dr. J. K. Barde & Research center was Tilak Ayurved Mahavidyalaya, Pune
(M.S.), India.

          Dr. Arora had taken clinical trials of use of Haritaki plant in patients of excess cholesterol level. Two groups were form one group with 78 patients which is treated with Haritaki & another group of 75 patients in which placebo medicine was used.

This was single blind trial.

Treatment group was given powder of Haritaki in the dose of 9 gm/day. In three divided doses after meal.

In placebo group starch capsules were given in the dose of 2 cap. (500 gm each tds) after meals. Vehicle was lukewarm water. Period of study was 6 wks. Lab investigations like serum cholesterol, LDL, HDL, Triglycerides, blood sugar were done.

          After analysis above research work is concluded as follows-

i)                   Powder of Haritaki i.e. Terminalia chebula 3 Gms ,TDS with Luke warm water ,for one & half month ,brings about a substantial reduction in the increase serum cholesterol level.

ii)                The drug should also weight reducing property.

iii)              LD50 of the drug is very high & so it is safe for prolonged use.


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